ALG6 antibody (N-Term)

Catalog No. ABIN2782789

The Rabbit Polyclonal anti-ALG6 antibody (ABIN2782789) specifically detects ALG6 in WB. The antibody is reactive with Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Rabbit, Cow, Horse, Guinea Pig and Saccharomyces cerevisiae samples.

Quick Overview for ALG6 antibody (N-Term) (ABIN2782789)

Target: ALG6 (Asparagine-Linked Glycosylation 6, alpha-1,3-Glucosyltransferase Homolog (ALG6))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Rabbit, Cow, Horse, Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALG6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ALG6 Antibody

Binding Specificity: N-Term

Purpose: ALG6 Antibody - N-terminal region

Sequence: YEAQRHWQEI TFNLPVKQWY FNSSDNNLQY WGLDYPPLTA YHSLLCAYVA

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against ALG6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ALG6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46927-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ALG6

Target: ALG6 (Asparagine-Linked Glycosylation 6, alpha-1,3-Glucosyltransferase Homolog (ALG6))

Alternative Name: ALG6

Background:

Background Information: ALG6 is a member of the ALG6/ALG8 glucosyltransferase family. It catalyzes the addition of the first glucose residue to the growing lipid-linked oligosaccharide precursor of N-linked glycosylation. Mutations in this gene encoding ALG6 are associated with congenital disorders of glycosylation type Ic.This gene encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of the first glucose residue to the growing lipid-linked oligosaccharide precursor of N-linked glycosylation. Mutations in this gene are associated with congenital disorders of glycosylation type Ic. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)

Alternative Symbols: CDG1C

Protein Name: Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase

Molecular Weight: 58kDa

Gene ID: 29929

NCBI Accession: NP_037471

UniProt: Q9Y672