ATP11B antibody (N-Term)

Catalog No. ABIN2782823

The Rabbit Polyclonal anti-ATP11B antibody (ABIN2782823) specifically detects ATP11B in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig, Pig and Zebrafish (Danio rerio) samples.

Quick Overview for ATP11B antibody (N-Term) (ABIN2782823)

Target: ATP11B (ATPase, Class VI, Type 11B (ATP11B))

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP11B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ATP11B Antibody

Binding Specificity: N-Term

Purpose: ATP11B Antibody - N-terminal region

Sequence: DIVRIAKDEI FPADLVLLSS DRLDGSCHVT TASLDGETNL KTHVAVPETA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against ATP11B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ATP11B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47046-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATP11B

Target: ATP11B (ATPase, Class VI, Type 11B (ATP11B))

Alternative Name: ATP11B

Background:

Background Information: P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-91 BI861412.1 1-91 92-104 AF156548.1 1-13 105-809 BC042180.1 105-809 810-1001 AF156548.1 719-910 1002-1244 BX489704.1 417-659 1245-1346 BF372979.1 79-180 1347-1791 BU431705.1 43-487 1792-4720 AB023173.1 22-2950 4721-6422 AL133061.1 2205-3906 6423-7314 AB023173.1 4651-5542 7315-7368 AL133061.1 4799-4852

Gene Name: ATPase, class VI, type 11B

Alternative Symbols: ATPIF, ATPIR

Protein Name: Probable phospholipid-transporting ATPase IF

Molecular Weight: 134kDa

Gene ID: 23200

NCBI Accession: NP_055431

UniProt: Q9Y2G3