LRRC8B antibody (N-Term)

Catalog No. ABIN2782846

The Rabbit Polyclonal anti-LRRC8B antibody has been validated for WB. It is suitable to detect LRRC8B in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit. There is 1 publication available.

Quick Overview for LRRC8B antibody (N-Term) (ABIN2782846)

Target: LRRC8B (Leucine Rich Repeat Containing 8 Family, Member B (LRRC8B))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC8B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LRRC8B Antibody

Binding Specificity: N-Term

Sequence: PSTSSRLEHF VAILHKCFDS PWTTRALSET VAEQSVRPLK LSKSKILLSS

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against LRRC8B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LRRC8B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 803 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-LRRC8B antibody (ABIN2782846)

Kubota, Kim, Sawada, Tokimasa, Fujisaki, Matsuda-Hashii, Ozono, Hara: "LRRC8 involved in B cell development belongs to a novel family of leucine-rich repeat proteins." in: FEBS letters, Vol. 564, Issue 1-2, pp. 147-52, (2004) (PubMed).

Target Details for LRRC8B

Target: LRRC8B (Leucine Rich Repeat Containing 8 Family, Member B (LRRC8B))

Alternative Name: LRRC8B

Background: The exact function of LRRC8B remains unknown.
Alias Symbols: KIAA0231, MGC42220, TA-LRRP, TALRRP
Protein Interaction Partner: CUL3,
Protein Size: 803

Molecular Weight: 92 kDa

Gene ID: 23507

NCBI Accession: NM_015350, NP_056165

UniProt: Q6P9F7