A4GNT antibody (N-Term)

Catalog No. ABIN2782874

There is 1 publication for this product available. The Rabbit Polyclonal anti-A4GNT antibody is suitable to detect A4GNT in samples from Human, Cow and Pig. It has been validated for WB.

Quick Overview for A4GNT antibody (N-Term) (ABIN2782874)

Target: A4GNT (alpha-1,4-N-Acetylglucosaminyltransferase (A4GNT))

Reactivity: Human, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This A4GNT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-A4GNT Antibody

Binding Specificity: N-Term

Purpose: A4GNT Antibody - N-terminal region

Sequence: LLLVCGFLYQ FTLKSSCLFC LPSFKSHQGL EALLSHRRGI VFLETSERME

Predicted Reactivity: Cow: 100%, Human: 100%, Pig: 83%

Characteristics: This is a rabbit polyclonal antibody against A4GNT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human A4GNT

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8094462

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-A4GNT antibody (ABIN2782874)

Ishizone, Maruta, Saito, Koide, Sugiyama, Nakayama, Miyagawa: "Efficacy of S-1 for patients with peritoneal metastasis of gastric cancer." in: Chemotherapy, Vol. 52, Issue 6, pp. 301-7, (2006) (PubMed).

Target Details for A4GNT

Target: A4GNT (alpha-1,4-N-Acetylglucosaminyltransferase (A4GNT))

Alternative Name: A4GNT

Background:

Background Information: A4GNT is a protein from the glycosyltransferase 32 family. The enzyme catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. It forms a unique glycan, GlcNAcalpha1-->4Galbeta-->R and is largely associated with the Golgi apparatus membrane.This gene encodes a protein from the glycosyltransferase 32 family. The enzyme catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. It forms a unique glycan, GlcNAcalpha1-->4Galbeta-->R and is largely associated with the Golgi apparatus membrane. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.This gene encodes a protein from the glycosyltransferase 32 family. The enzyme catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. It forms a unique glycan, GlcNAcalpha1-->4Galbeta-->R and is largely associated with the Golgi apparatus membrane. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

Gene Name: Alpha-1,4-N-acetylglucosaminyltransferase

Alternative Symbols: alpha4GnT

Protein Name: Alpha-1,4-N-acetylglucosaminyltransferase

Molecular Weight: 39kDa

Gene ID: 51146

NCBI Accession: NP_057245

UniProt: Q9UNA3