IL1RL1 antibody (N-Term)

Catalog No. ABIN2782880

Product Details anti-IL1RL1 Antibody

Target: IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1RL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RQGKPSYTVD WYYSQTNKSI PTQERNRVFA SGQLLKFLPA AVADSGIYTC

Predicted Reactivity: Dog: 79%, Human: 100%, Mouse: 79%

Characteristics: This is a rabbit polyclonal antibody against IL1RL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IL1RL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 556 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IL1RL1

Target: IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

Alternative Name: IL1RL1 (IL1RL1 Products)

Background: IL1RL1 is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants.The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants.
Alias Symbols: DER4, FIT-1, MGC32623, ST2, ST2L, ST2V, T1, IL33R
Protein Interaction Partner: CLEC7A, IRAK4, TRAF6, MYD88, IRAK1, APP, IL33, TIRAP, TMED1,
Protein Size: 556

Molecular Weight: 61 kDa

Gene ID: 9173

NCBI Accession: NM_016232, NP_057316

UniProt: Q01638