DNAJB11 antibody (C-Term)

Catalog No. ABIN2782885

The Rabbit Polyclonal anti-DNAJB11 antibody is suitable to detect DNAJB11 in samples from Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio) and Rabbit. It has been validated for WB.

Quick Overview for DNAJB11 antibody (C-Term) (ABIN2782885)

Target: DNAJB11 (DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11))

Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAJB11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DNAJB11 Antibody

Binding Specificity: C-Term

Purpose: DNAJB11 Antibody - C-terminal region

Sequence: FDNNNIKGSL IITFDVDFPK EQLTEEAREG IKQLLKQGSV QKVYNGLQGY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against DNAJB11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DNAJB11

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47245-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DNAJB11

Target: DNAJB11 (DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11))

Alternative Name: DNAJB11

Background:

Background Information: DNAJB11 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a C-terminal cysteine-rich region.DNAJB11 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a C-terminal cysteine-rich region (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1723 BC046500.1 710-2432

Gene Name: DnaJ (Hsp40) homolog, subfamily B, member 11

Alternative Symbols: DJ9, EDJ, Dj-9, ERj3, PKD6, ABBP2, ERdj3, ERj3p, ABBP-2, UNQ537, PRO1080

Protein Name: DnaJ homolog subfamily B member 11

Molecular Weight: 40kDa

Gene ID: 51726

NCBI Accession: NP_057390

UniProt: Q9UBS4

Pathways: ER-Nucleus Signaling