LAX1 antibody (Middle Region)

Catalog No. ABIN2782914

This Rabbit Polyclonal antibody specifically detects LAX1 in WB. It exhibits reactivity toward Human, Rat and Cow.

Quick Overview for LAX1 antibody (Middle Region) (ABIN2782914)

Target: LAX1 (Lymphocyte Transmembrane Adaptor 1 (LAX1))

Reactivity: Human, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LAX1 Antibody

Binding Specificity: Middle Region

Sequence: LFVLPSTQKL EFTEERDEGC GDAGDCTSLY SPGAEDSDSL SNGEGSSQIS

Predicted Reactivity: Cow: 79%, Human: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against LAX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LAX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 398 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LAX1

Target: LAX1 (Lymphocyte Transmembrane Adaptor 1 (LAX1))

Alternative Name: LAX1

Background: LAX1 is a single-pass type III membrane protein. It negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.
Alias Symbols: FLJ20340, LAX
Protein Interaction Partner: STAMBPL1, GRB7, NDN, UBC, GRAP2, SYK, ZAP70, LCK, GRB2,
Protein Size: 398

Molecular Weight: 44 kDa

Gene ID: 54900

NCBI Accession: NM_017773, NP_060243

UniProt: Q8IWV1

Pathways: Production of Molecular Mediator of Immune Response