LAX1 antibody (Middle Region)

Catalog No. ABIN2782914

Product Details anti-LAX1 Antibody

Target: LAX1 (Lymphocyte Transmembrane Adaptor 1 (LAX1))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAX1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LFVLPSTQKL EFTEERDEGC GDAGDCTSLY SPGAEDSDSL SNGEGSSQIS

Predicted Reactivity: Cow: 79%, Human: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against LAX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LAX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 398 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LAX1

Target: LAX1 (Lymphocyte Transmembrane Adaptor 1 (LAX1))

Alternative Name: LAX1 (LAX1 Products)

Synonyms: LAX antibody, A530029E09 antibody, E430019B13Rik antibody, lymphocyte transmembrane adaptor 1 antibody, LAX1 antibody, Lax1 antibody

Background: LAX1 is a single-pass type III membrane protein. It negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.
Alias Symbols: FLJ20340, LAX
Protein Interaction Partner: STAMBPL1, GRB7, NDN, UBC, GRAP2, SYK, ZAP70, LCK, GRB2,
Protein Size: 398

Molecular Weight: 44 kDa

Gene ID: 54900

NCBI Accession: NM_017773, NP_060243

UniProt: Q8IWV1

Pathways: Production of Molecular Mediator of Immune Response