CHST11 antibody (C-Term)

Catalog No. ABIN2782968

Product Details anti-CHST11 Antibody

Target: CHST11 (Carbohydrate (Chondroitin 4) Sulfotransferase 11 (CHST11))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHST11 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FEEFVAYLID PHTQREEPFN EHWQTVYSLC HPCHIHYDLV GKYETLEEDS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against Chst11. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Rat

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 352 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHST11

Target: CHST11 (Carbohydrate (Chondroitin 4) Sulfotransferase 11 (CHST11))

Alternative Name: Chst11 (CHST11 Products)

Background: Chst11 catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Chst11 can also sulfate Gal residues in desulfated dermatan sulfate. Chst11 preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.
Alias Symbols: C4ST1, Chst11
Protein Size: 352

Molecular Weight: 38 kDa

Gene ID: 314694

NCBI Accession: NM_001108079, NP_001101549

UniProt: P69478

Pathways: Glycosaminoglycan Metabolic Process