KRT23 antibody (Middle Region)

Catalog No. ABIN2782975

The Rabbit Polyclonal anti-KRT23 antibody is suitable to detect KRT23 in samples from Human, Horse, Dog and Guinea Pig. It has been validated for WB and IHC.

Quick Overview for KRT23 antibody (Middle Region) (ABIN2782975)

Target: KRT23 (Keratin 23 (KRT23))

Reactivity: Human, Horse, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KRT23 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-KRT23 Antibody

Binding Specificity: Middle Region

Purpose: KRT23 Antibody - middle region

Sequence: IKTHLEKEIT TYRRLLEGES EGTREESKSS MKVSATPKIK AITQETINGR

Predicted Reactivity: Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against KRT23. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KRT23

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47466-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for KRT23

Target: KRT23 (Keratin 23 (KRT23))

Alternative Name: KRT23

Background:

Background Information: KRT23 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains.The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.

Gene Name: Keratin 23 (histone deacetylase inducible)

Alternative Symbols: K23, CK23, HAIK1

Protein Name: Keratin, type I cytoskeletal 23

Molecular Weight: 48kDa

Gene ID: 25984

NCBI Accession: NP_056330

UniProt: Q9C075