UNCX antibody (N-Term)

Catalog No. ABIN2783014

Cited in 1 publication. The Rabbit Polyclonal anti-UNCX antibody (ABIN2783014) specifically detects UNCX in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog and Pig samples.

Quick Overview for UNCX antibody (N-Term) (ABIN2783014)

Target: UNCX (UNC Homeobox (UNCX))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNCX antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UNCX Antibody

Binding Specificity: N-Term

Purpose: UNCX Antibody - N-terminal region

Sequence: LLPAACGVGG DGQPFKLSDS GDPDKESPGC KRRRTRTNFT GWQLEELEKA

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against UNCX. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UNCX

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47548-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-UNCX antibody (ABIN2783014)

Chen, Huang, Wang, Guo, Du, Ma, Zhao, Pan, Gui, Yuan, Liu, Song, Wang, He, Lei, Gao: "Characterization of zebrafish Pax1b and Pax9 in fin bud development." in: BioMed research international, Vol. 2014, pp. 309385, (2014) (PubMed).

Target Details for UNCX

Target: UNCX (UNC Homeobox (UNCX))

Alternative Name: UNCX

Background:

Background Information: UNCX is a transcription factor involved in somitogenesis and neurogenesis. It is required for the maintenance and differentiation of particular elements of the axial skeleton. It may act upstream of PAX9. UNCX plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions.

Gene Name: UNC homeobox

Alternative Symbols: UNCX4.1

Protein Name: Homeobox protein unc-4 homolog

Molecular Weight: 54kDa

Gene ID: 340260

NCBI Accession: NP_001073930

UniProt: A6NJT0