VAMP7 antibody (C-Term)

Catalog No. ABIN2783037

This Rabbit Polyclonal antibody specifically detects VAMP7 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep and Zebrafish (Danio rerio).

Quick Overview for VAMP7 antibody (C-Term) (ABIN2783037)

Target: VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAMP7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-VAMP7 Antibody

Binding Specificity: C-Term

Purpose: Vamp7 Antibody - C-terminal region

Sequence: DELKGIMVRN IDLVAQRGER LELLIDKTEN LVDSSVTFKT TSRNLARAMC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Vamp7. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47593-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for VAMP7

Target: VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))

Alternative Name: Vamp7

Background:

Background Information: Vamp7 is involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Vamp7 is required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion.Vamp7 is required for calcium regulated lysosomal exocytosis. Vamp7 is involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi.Vamp7 is required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Vamp7 is also required for focal exocytosis of late endocytic vesicles during phagosome formation.

Gene Name: Vesicle-associated membrane protein 7

Alternative Symbols: Syb, VAM, Sybl1, VAMP-7, TI-VAMP

Protein Name: Vesicle-associated membrane protein 7

Molecular Weight: 25kDa

Gene ID: 20955

NCBI Accession: NP_035645

UniProt: P70280