MAFA antibody (N-Term)

Catalog No. ABIN2783127

The Rabbit Polyclonal anti-MAFA antibody (ABIN2783127) specifically detects MAFA in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Guinea Pig and Pig samples.

Quick Overview for MAFA antibody (N-Term) (ABIN2783127)

Target: MAFA (Transcription Factor MafA (MAFA))

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAFA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAFA Antibody

Binding Specificity: N-Term

Purpose: MAFA Antibody - N-terminal region

Sequence: KPALEDLYWM SGYQHHLNPE ALNLTPEDAV EALIGSGHHG AHHGAHHPAA

Cross-Reactivity: Cow: 100%, Dog: 79%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 83%

Predicted Reactivity: Cow: 100%, Dog: 79%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against MAFA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAFA

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47760-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAFA

Target: MAFA (Transcription Factor MafA (MAFA))

Alternative Name: MAFA

Background:

Background Information: MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS).MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS, MIM 176730) (Olbrot et al., 2002 [PubMed 12011435]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1062 AC105118.23 99326-100387 c

Gene Name: V-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)

Alternative Symbols: INSDM, hMafA, RIPE3b1

Protein Name: Transcription factor MafA

Molecular Weight: 37kDa

Gene ID: 389692

NCBI Accession: NP_963883

UniProt: Q8NHW3

Pathways: Hormone Transport