Nephronectin antibody (Middle Region)

Catalog No. ABIN2783147

This Rabbit Polyclonal antibody specifically detects Nephronectin in WB. It exhibits reactivity toward Human, Mouse, Dog, Rat, Guinea Pig, Horse, Cow and Rabbit.

Quick Overview for Nephronectin antibody (Middle Region) (ABIN2783147)

Target: Nephronectin (NPNT)

Reactivity: Human, Mouse, Dog, Rat, Guinea Pig, Horse, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nephronectin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Nephronectin Antibody

Binding Specificity: Middle Region

Purpose: NPNT Antibody - middle region

Sequence: TTGLTTIAPA ASTPPGGITV DNRVQTDPQK PRGDVFIPRQ PSNDLFEIFE

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NPNT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NPNT

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47815-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Nephronectin

Target: Nephronectin (NPNT)

Alternative Name: NPNT

Background:

Background Information: NPNT is a functional ligand of integrin alpha-8/beta-1 in kidney development. It regulates with integrin alpha-8/beta-1 the expression of GDNF which is essential for kidney development. It may also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins.

Gene Name: Nephronectin

Alternative Symbols: POEM, EGFL6L

Protein Name: Nephronectin

Molecular Weight: 62kDa

Gene ID: 255743

NCBI Accession: NP_001028219

UniProt: Q6UXI9