UXT antibody (N-Term)

Catalog No. ABIN310955

The Rabbit Polyclonal anti-UXT antibody has been validated for WB. It is suitable to detect UXT in samples from Human, Rat, Dog, Rabbit, Cow, Horse and Guinea Pig.

Quick Overview for UXT antibody (N-Term) (ABIN310955)

Target: UXT (Ubiquitously-Expressed, Prefoldin-Like Chaperone (UXT))

Reactivity: Human, Rat, Dog, Rabbit, Cow, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UXT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UXT Antibody

Binding Specificity: N-Term

Sequence: MATPPKRRAV EATGEKVLRY ETFISDVLQR DLRKVLDHRD KVYEQLAKYL

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against UXT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UXT

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 157 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UXT

Target: UXT (Ubiquitously-Expressed, Prefoldin-Like Chaperone (UXT))

Alternative Name: UXT

Background: UXT is a novel protein which is highly conserved in mouse. It interacts with the N-terminus of the androgen receptor and plays a role in facilitating receptor-induced transcriptional activation. It is also likely to be involved in tumorigenesis as it is abundantly expressed in tumor tissues.This gene encodes a novel protein which is highly conserved in mouse. It interacts with the N-terminus of the androgen receptor and plays a role in facilitating receptor-induced transcriptional activation. It is also likely to be involved in tumorigenesis as it is abundantly expressed in tumor tissues. This gene is part of a gene cluster on chromosome Xp11.23. Alternative splicing results in 2 transcript variants encoding different isoforms.This gene encodes a novel protein which is highly conserved in mouse. It interacts with the N-terminus of the androgen receptor and plays a role in facilitating receptor-induced transcriptional activation. It is also likely to be involved in tumorigenesis as it is abundantly expressed in tumor tissues. This gene is part of a gene cluster on chromosome Xp11.23. Alternative splicing results in 2 transcript variants encoding different isoforms.
Alias Symbols: ART-27, STAP1
Protein Interaction Partner: NOTCH2NL, KRTAP10-8, KRTAP10-7, KRT40, PAK7, SIAH1, KRT31, TRIM63, TRIM55, RPAP3, Vhl, AR, UBC, Ctbp2, RUNX1, APP, URI1, SVIL, RPAP2, RUVBL2, CECR2, LRPPRC, LSM1, RCAN1, GLE1, RBL2, RBL1, E2F1, E2F2, E2F3, E2F4, SKP2,
Protein Size: 157

Molecular Weight: 18 kDa

Gene ID: 8409

NCBI Accession: NM_004182, NP_004173

UniProt: Q9UBK9

Pathways: Unfolded Protein Response