NDRG1 antibody (N-Term)

Catalog No. ABIN2783177

The Rabbit Polyclonal anti-NDRG1 antibody (ABIN2783177) specifically detects NDRG1 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Rabbit, Horse, Pig and Guinea Pig samples.

Quick Overview for NDRG1 antibody (N-Term) (ABIN2783177)

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Horse, Pig, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDRG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NDRG1 Antibody

Binding Specificity: N-Term

Sequence: MSREMQDVDL AEVKPLVEKG ETITGLLQEF DVQEQDIETL HGSVHVTLCG

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NDRG1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NDRG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 394 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NDRG1

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Alternative Name: NDRG1

Background: NDRG1 is a member of the N-myc downregulated protein family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. Mutation in its gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom.This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. Mutation in this gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom.
Alias Symbols: CAP43, CMT4D, DRG1, GC4, HMSNL, NDR1, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5
Protein Interaction Partner: TAF9, SUMO2, BCL2L11, CUL2, HSPA4, EED, SUZ12, FTO, ACOT7, GSR, NAMPT, DPP3, KYNU, DDX39B, EIF4H, PGD, PEPD, MVD, LDHA, MLH1, IGBP1, CLNS1A, ANXA5, SPAG9, CNDP2, PABPC1, RUVBL2, SEC23A, AP1M2, COPB2, VCP, TLE3, TARS, SHMT2, RPS26, RPS20, RPS16, RPS9, RPS8
Protein Size: 394

Molecular Weight: 43 kDa

Gene ID: 10397

NCBI Accession: NM_006096, NP_006087

UniProt: Q92597