NDRG1 antibody
Quick Overview for NDRG1 antibody (ABIN7268783)
Target
See all NDRG1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- NDRG1 Rabbit mAb
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- A synthesized peptide derived from human NDRG1
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))
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Alternative Name
- NDRG1
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Background
- This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],CAP43, CMT4D, DRG-1, DRG1, GC4, HMSNL, NDR1, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5,Angiogenesis,Cancer,Cardiovascular,Epigenetics & Nuclear Signaling,Invasion and Metastasis,Neurodegenerative Diseases,Neuroscience,Protein phosphorylation,Signal Transduction,NDRG1
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Molecular Weight
- 43kDa
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Gene ID
- 10397
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UniProt
- Q92597
Target
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