PPP2R5A antibody (N-Term)

Catalog No. ABIN2783198

The Rabbit Polyclonal anti-PPP2R5A antibody has been validated for WB. It is suitable to detect PPP2R5A in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Goat and Zebrafish (Danio rerio).

Quick Overview for PPP2R5A antibody (N-Term) (ABIN2783198)

Target: PPP2R5A (Protein Phosphatase 2, Regulatory Subunit B' alpha (PPP2R5A))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Goat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R5A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPP2R5A Antibody

Binding Specificity: N-Term

Sequence: YVSTNRGVIV ESAYSDIVKM ISANIFRTLP PSDNPDFDPE EDEPTLEASW

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PPP2R5A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPP2R5A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 486 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPP2R5A

Target: PPP2R5A (Protein Phosphatase 2, Regulatory Subunit B' alpha (PPP2R5A))

Alternative Name: PPP2R5A

Background: PPP2R5A belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity.The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: B56A, MGC131915, PR61A
Protein Interaction Partner: ESPL1, PTTG1, UBC, CBX5, Mdm2, Ccng1, PYGM, NEK1, CHEK2, Soga1, Sgol1, Sgol2, Ppp2r1a, AXIN1, MYC, GNL3, TP63, SHC1, CSNK1A1, EIF2AK2, APC, NOS3, MAPT, BEST1, BCL2, JAK2, CTLA4, PPP2R1B, PPP2CA, PPP2R5C,
Protein Size: 486

Molecular Weight: 56 kDa

Gene ID: 5525

NCBI Accession: NM_006243, NP_006234

UniProt: Q15172

Pathways: PI3K-Akt Signaling