ALDOA antibody (N-Term)

Catalog No. ABIN2783231

Product Details anti-ALDOA Antibody

Target: ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Cow, Horse, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDOA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MPYQYPALTP EQKKELSDIA HRIVAPGKGI LAADESTGSI AKRLQSIGTE

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 93%, Sheep: 82%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against ALDOA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ALDOA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 364 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ALDOA antibody (ABIN2783231)

Braceland, McLoughlin, Tinsley, Wallace, Cockerill, McLaughlin, Eckersall: "Serum enolase: a non-destructive biomarker of white skeletal myopathy during pancreas disease (PD) in Atlantic salmon Salmo salar L." in: Journal of fish diseases, Vol. 38, Issue 9, pp. 821-31, (2015) (PubMed).

Mao, Yang, Xu, Sang, Lu, Yang, Zhang, Zhong, Huang, Zhang: "[Significance of Golgi glycoprotein 73, a new tumor marker in diagnosis of hepatocellular carcinoma: a primary study]." in: Zhonghua yi xue za zhi, Vol. 88, Issue 14, pp. 948-51, (2008) (PubMed).

Target Details for ALDOA

Target: ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))

Alternative Name: ALDOA (ALDOA Products)

Synonyms: ALDA antibody, GSD12 antibody, aldoa antibody, cb79 antibody, sb:cb79 antibody, wu:fa28b10 antibody, wu:fb10b11 antibody, ALDOA antibody, Aldo-1 antibody, Aldo1 antibody, RNALDOG5 antibody, hm:zeh0036 antibody, zgc:77696 antibody, aldolase, fructose-bisphosphate A antibody, aldolase a, fructose-bisphosphate, a antibody, aldolase, fructose-bisphosphate A S homeolog antibody, aldolase A, fructose-bisphosphate antibody, aldolase a, fructose-bisphosphate, b antibody, ALDOA antibody, aldoaa antibody, aldoa antibody, aldoa.S antibody, Aldoa antibody, aldoab antibody

Background: ALDOA is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia.This gene product, Aldolase A (fructose-bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants which encode the same protein.
Alias Symbols: ALDA, MGC10942, MGC17716, MGC17767, GSD12
Protein Interaction Partner: HUWE1, UBC, IFNA4, FUS, ALDOC, ALDOA, SUMO2, SUMO3, MDM2, ADRB2, SUZ12, TNPO3, CS, RAD52, VCPKMT, PIAS4, GALNT6, IQCB1, VCAM1, MLH1, ITGA4, HSP90AB1, HSP90AA1, FN1, ATF2, BCAT2, ALDOB, LIG4, PGK1, LGALS1, HSPD1, AKT1, MYOC, CDK2, CUL2, CUL3, CUL4B, ISG15,
Protein Size: 364

Molecular Weight: 39 kDa

Gene ID: 226

NCBI Accession: NM_000034, NP_000025

UniProt: P04075

Pathways: Ribonucleoside Biosynthetic Process