OAT antibody (C-Term)

Catalog No. ABIN2783234

The Rabbit Polyclonal anti-OAT antibody has been validated for WB and IHC. It is suitable to detect OAT in samples from Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig and Zebrafish (Danio rerio). There is 1 publication available.

Quick Overview for OAT antibody (C-Term) (ABIN2783234)

Target: OAT (Ornithine Aminotransferase (OAT))

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OAT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-OAT Antibody

Binding Specificity: C-Term

Sequence: VRGKGLLNAI VIKETKDWDA WKVCLRLRDN GLLAKPTHGD IIRFAPPLVI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against OAT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human OAT

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 439 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-OAT antibody (ABIN2783234)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for OAT

Target: OAT (Ornithine Aminotransferase (OAT))

Background: OAT is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy.This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme is the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-42 DB459793.1 27-68 43-2062 BC016928.1 1-2020 2063-2066 M12267.1 2010-2013
Alias Symbols: DKFZp781A11155, HOGA, OKT, GACR, OATASE
Protein Interaction Partner: FUS, HUWE1, SUMO2, STAU1, UBC, ADRB2, ATF2, CTSA, FBXO6, UBQLN4, CDK2, SIRT7, NUDT3, HDAC5, MYC, ICT1, OTUD4, DMWD, SLC35F6, OAT, EIF6,
Protein Size: 439

Molecular Weight: 45 kDa

Gene ID: 4942

NCBI Accession: NM_000274, NP_000265

UniProt: P04181