GBAS antibody (Middle Region)

Catalog No. ABIN2783257

This Rabbit Polyclonal antibody specifically detects GBAS in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Horse and Zebrafish (Danio rerio)and has been mentioned in 1 publication.

Quick Overview for GBAS antibody (Middle Region) (ABIN2783257)

Target: GBAS (Glioblastoma Amplified Sequence (GBAS))

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBAS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GBAS Antibody

Binding Specificity: Middle Region

Sequence: VPRSGPNIYE LRSYQLRPGT MIEWGNYWAR AIRFRQDGNE AVGGFFSQIG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against GBAS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GBAS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 286 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-GBAS antibody (ABIN2783257)

Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

Target Details for GBAS

Target: GBAS (Glioblastoma Amplified Sequence (GBAS))

Alternative Name: GBAS

Background: Chromosomal region 7p12, which contains GBAS, is amplified in approximately 40 % of glioblastomas, the most common and malignant form of central nervous system tumor.The predicted 286-amino acid protein contains a signal peptide, a transmembrane domain, and 2 tyrosine phosphorylation sites. The GBAS transcript is expressed most abundantly in heart and skeletal muscle. GBAS protein might be involved in vesicular transport.Chromosomal region 7p12, which contains GBAS, is amplified in approximately 40 % of glioblastomas, the most common and malignant form of central nervous system tumor.The predicted 286-amino acid protein contains a signal peptide, a transmembrane domain, and 2 tyrosine phosphorylation sites. The GBAS transcript is expressed most abundantly in heart and skeletal muscle. GBAS protein might be involved in vesicular transport.
Alias Symbols: NIPSNAP2
Protein Interaction Partner: VCP, UBC, SUMO1, NEDD8, AMOT, CDH1, CUL3, EBNA-LP, PRKCI, MAP1LC3A, MAP1LC3B, LARS, ANKFY1, GABARAPL1, GANAB, GABARAPL2, GABARAP, DDX39A, NAMPT, NPEPPS, LONP1, MTA2, SQSTM1, NIPSNAP1, WARS, TARS, PRKDC, PGK1, PFKP, PFAS, PA2G4, HK1, HADHA, FOXO3, FKBP4, A
Protein Size: 286

Molecular Weight: 34 kDa

Gene ID: 2631

NCBI Accession: NM_001483, NP_001474

UniProt: O75323

Pathways: Ribonucleoside Biosynthetic Process