Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) (N-Term) antibody

Catalog No. ABIN2783321

This anti- antibody is a Rabbit Polyclonal antibody detecting in WB and IHC. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). This Primary Antibody has been cited in 1 publication.

Quick Overview for Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) (N-Term) antibody (ABIN2783321)

Target: Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details

Binding Specificity: N-Term

Sequence: MSVPAFIDIS EEDQAAELRA YLKSKGAEIS EENSEGGLHV DLAQIIEACD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against EIF3M. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EIF3M

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 374 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

Cheshenko, Trepanier, Segarra, Fuller, Herold: "HSV usurps eukaryotic initiation factor 3 subunit M for viral protein translation: novel prevention target." in: PLoS ONE, Vol. 5, Issue 7, pp. e11829, (2010) (PubMed).

Target Details

Target: Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)

Alternative Name: EIF3M

Background: EIF3M is a broadly expressed protein containing putative membrane fusion domains that acts as a receptor or coreceptor for entry of herpes simplex virus (HSV).HFLB5 encodes a broadly expressed protein containing putative membrane fusion domains that acts as a receptor or coreceptor for entry of herpes simplex virus (HSV) (Perez et al., 2005 [PubMed 15919898]).[supplied by OMIM].
Alias Symbols: B5, FLJ29030, GA17, PCID1, hfl-B5
Protein Interaction Partner: HUWE1, FAM96B, UBC, SUMO2, rev, SRPK1, EXOSC10, NPM1, MMS19, gag-pol, EIF3D, EIF3F, EIF3L, EIF3K, EIF3I, EIF3H, EIF3G, EIF3C, EIF3B, EIF3A, EIF3E, APP, TADA2A, EIF1B, EIF4A2,
Protein Size: 374

Molecular Weight: 42 kDa

Gene ID: 10480

NCBI Accession: NM_006360, NP_006351

UniProt: Q7L2H7

Pathways: Ribonucleoprotein Complex Subunit Organization