Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) (AA 2-374) antibody

Catalog No. ABIN7152172

Product Details

Target: Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)

Binding Specificity: AA 2-374

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Eukaryotic translation initiation factor 3 subunit M protein (2-374AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)

Alternative Name: EIF3M (EIF3M Products)

Synonyms: ga17 antibody, pcid1 antibody, hfl-b5 antibody, tango7 antibody, MGC69424 antibody, PCID1 antibody, DKFZp459D197 antibody, Ga17 antibody, Pcid1 antibody, Tango7 antibody, B5 antibody, TANGO7 antibody, hfl-B5 antibody, GA17 antibody, fa16c10 antibody, wu:fa16c10 antibody, wu:fc41f09 antibody, zgc:63996 antibody, HFL-B5 antibody, RGD1565840 antibody, eukaryotic translation initiation factor 3 subunit M antibody, eukaryotic translation initiation factor 3, subunit M antibody, eukaryotic translation initiation factor 3 subunit M S homeolog antibody, eif3m antibody, EIF3M antibody, Eif3m antibody, eif3m.S antibody

Target Type: Viral Protein

Background:

Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2).

Aliases: B5 antibody, B5 receptor antibody, Dendritic cell protein antibody, eIF3m antibody, EIF3M_HUMAN antibody, Eukaryotic translation initiation factor 3 subunit M antibody, Fetal lung protein B5 antibody, FLJ29030 antibody, GA17 antibody, hfl B5 antibody, hFL-B5 antibody, PCI domain containing 1 (herpesvirus entry mediator) antibody, PCI domain-containing protein 1 antibody, PCID1 antibody, TANGO7 antibody

UniProt: Q7L2H7

Pathways: Ribonucleoprotein Complex Subunit Organization