GRHPR antibody (N-Term)

Catalog No. ABIN2783330

This Rabbit Polyclonal antibody specifically detects GRHPR in WB and IHC. It exhibits reactivity toward Human, Rat, Dog, Pig, Horse and Rabbit.It has been mentioned in 1 publication

Quick Overview for GRHPR antibody (N-Term) (ABIN2783330)

Target: GRHPR (Glyoxylate Reductase/hydroxypyruvate Reductase (GRHPR))

Reactivity: Human, Rat, Dog, Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRHPR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GRHPR Antibody

Binding Specificity: N-Term

Purpose: GRHPR Antibody - N-terminal region

Sequence: EPIPAKELER GVAGAHGLLC LLSDHVDKRI LDAAGANLKV ISTMSVGIDH

Predicted Reactivity: Dog: 100%, Horse: 86%, Human: 100%, Pig: 79%, Rabbit: 93%, Rat: 91%

Characteristics: This is a rabbit polyclonal antibody against GRHPR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GRHPR

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48317-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-GRHPR antibody (ABIN2783330)

Takayama, Nagata, Ozono, Nonomura, Cramer: "A novel mutation in the GRHPR gene in a Japanese patient with primary hyperoxaluria type 2." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 22, Issue 8, pp. 2371-4, (2007) (PubMed).

Target Details for GRHPR

Target: GRHPR (Glyoxylate Reductase/hydroxypyruvate Reductase (GRHPR))

Alternative Name: GRHPR

Background:

Background Information: GRHPR is an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene.This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Glyoxylate reductase/hydroxypyruvate reductase

Alternative Symbols: PH2, GLXR, GLYD

Protein Name: Glyoxylate reductase/hydroxypyruvate reductase

Molecular Weight: 36kDa

Gene ID: 9380

NCBI Accession: NP_036335

UniProt: Q9UBQ7