COQ8A antibody (C-Term)

Catalog No. ABIN2783346

The Rabbit Polyclonal anti-COQ8A antibody (ABIN2783346) specifically detects COQ8A in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) and Saccharomyces cerevisiae samples.

Quick Overview for COQ8A antibody (C-Term) (ABIN2783346)

Target: COQ8A (Coenzyme Q8A (COQ8A))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COQ8A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COQ8A Antibody

Binding Specificity: C-Term

Purpose: COQ8A Antibody - C-terminal region

Sequence: LVLCLRELFE FHFMQTDPNW SNFFYDPQQH KVALLDFGAT REYDRSFTDL

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against ADCK3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human ADCK3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48386-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for COQ8A

Target: COQ8A (Coenzyme Q8A (COQ8A))

Alternative Name: COQ8A

Background:

Background Information: This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found, however, their full-length nature has not been determined.

Gene Name: coenzyme Q8A

Alternative Symbols: COQ8, ADCK3, ARCA2, CABC1, SCAR9, COQ10D4

Protein Name: atypical kinase COQ8A, mitochondrial

Molecular Weight: 54kDa

Gene ID: 56997

NCBI Accession: NP_064632

UniProt: Q8NI60