MPST antibody (Mercaptopyruvate Sulfurtransferase) (Middle Region)

Details for Product anti-MPST Antibody No. ABIN2783349
Antigen
  • MST
  • TST2
  • Mst
  • mst
  • tst
  • tst2
  • fa96h11
  • mpst
  • wu:fa96h11
  • mercaptopyruvate sulfurtransferase
  • zgc:162544
  • mercaptopyruvate sulfurtransferase L homeolog
  • mercaptopyruvate sulfurtransferase S homeolog
  • MPST
  • Mpst
  • mpst
  • zgc:162544
  • sseA
  • mpst.L
  • mpst.S
Epitope
Middle Region
6
4
3
3
3
2
2
2
1
1
Reactivity
Cow (Bovine), Dog (Canine), Goat, Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
29
6
2
1
1
1
1
1
1
Host
Rabbit
26
7
Clonality
Polyclonal
Conjugate
This MPST antibody is un-conjugated
1
1
1
Application
Western Blotting (WB)
26
9
6
6
6
4
2
1
1
Options
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human MPST
Blocking Peptide Blocking peptide for this product available: ABIN980220
Sequence DPAFIKTYED IKENLESRRF QVVDSRATGR FRGTEPEPRD GIEPGHIPGT
Predicted Reactivity Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%
Characteristics This is a rabbit polyclonal antibody against MPST. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Plasmids, Primers & others Plasmids, Primers & others MPST products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name MPST (MPST Antibody Abstract)
Background MPST transfer of a sulfur ion to cyanide or to other thiol compounds. MPST also has weak rhodanese activity. MPST may have a role in cyanide degradation or in thiosulfate biosynthesis.This gene encodes a protein which can function as a monomer or as a disulfide-linked homodimer and which catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cyanide degradation and in thiosulfate biosynthesis. The encoded cytoplasmic protein is a member of the rhodanese family but is not rhodanese itself, which is a mitochondrial protein. Alternatively spliced transcript variants encoding the same protein have been identified.
Alias Symbols: MGC24539, MST, TST2
Protein Interaction Partner: UBC, NEDD8, TMEM189, S100A16, NADK2, SEPT11, TIMM9, YKT6, SEC22B, VAPB, UQCRFS1, UPP1, TPI1, NDUFV1, ANXA4, RAE1,
Protein Size: 297
Molecular Weight 33 kDa
Gene ID 4357
NCBI Accession NM_021126, NP_066949
UniProt P25325
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 297 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Mercaptopyruvate Sulfurtransferase (MPST) (Middle Region) antibody (ABIN2783349) WB Suggested Anti-MPST Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Posit...
Western Blotting (WB) image for anti-Mercaptopyruvate Sulfurtransferase (MPST) (Middle Region) antibody (ABIN2783349) Host: Rabbit Target Name: MPST Sample Type: Lane 1: 40 ug Human Liver lysate La...
Product cited in: Cui, Navneet, Wang, Roon, Chen, Xian, Smith: "Analysis of MTHFR, CBS, Glutathione, Taurine, and Hydrogen Sulfide Levels in Retinas of Hyperhomocysteinemic Mice." in: Investigative ophthalmology & visual science, Vol. 58, Issue 4, pp. 1954-1963, 2017 (PubMed).

Otani, Nagaoka, Omae, Tanano, Kamiya, Ono, Hein, Kuo, Yoshida: "Histamine-Induced Dilation of Isolated Porcine Retinal Arterioles: Role of Endothelium-Derived Hyperpolarizing Factor." in: Investigative ophthalmology & visual science, Vol. 57, Issue 11, pp. 4791-8, 2016 (PubMed).

Lo, Tsai, Tsai, Hua, Tsai, Huang, Tsai, Lai: "Identification of over-expressed proteins in oral squamous cell carcinoma (OSCC) patients by clinical proteomic analysis." in: Clinica chimica acta; international journal of clinical chemistry, Vol. 376, Issue 1-2, pp. 101-7, 2006 (PubMed).

Background publications Billaut-Laden, Rat, Allorge, Crunelle-Thibaut, Cauffiez, Chevalier, Lo-Guidice, Broly: "Evidence for a functional genetic polymorphism of the human mercaptopyruvate sulfurtransferase (MPST), a cyanide detoxification enzyme." in: Toxicology letters, Vol. 165, Issue 2, pp. 101-11, 2006 (PubMed).

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