MTR antibody (C-Term)

Catalog No. ABIN2783384

The Rabbit Polyclonal anti-MTR antibody (ABIN2783384) specifically detects MTR in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Horse, Rabbit and Guinea Pig samples.

Quick Overview for MTR antibody (C-Term) (ABIN2783384)

Target: MTR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase (MTR))

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MTR Antibody

Binding Specificity: C-Term

Purpose: MTR Antibody - C-terminal region

Sequence: GSEQLDVADL RRLRYKGIRP APGYPSQPDH TEKLTMWRLA DIEQSTGIRL

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MTR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MTR

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48473-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MTR

Target: MTR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase (MTR))

Alternative Name: MTR

Background:

Background Information: MTR is the enzyme 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G. MTR encodes the enzyme 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: 5-methyltetrahydrofolate-homocysteine methyltransferase

Alternative Symbols: MS, HMAG, cblG

Protein Name: Methionine synthase

Molecular Weight: 141 kDa

Gene ID: 4548

NCBI Accession: NP_000245

UniProt: Q99707

Pathways: Methionine Biosynthetic Process