OXCT1 antibody (N-Term)

Catalog No. ABIN2783387

This Rabbit Polyclonal antibody specifically detects OXCT1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Dog, Horse and Pig.

Quick Overview for OXCT1 antibody (N-Term) (ABIN2783387)

Target: OXCT1 (3-Oxoacid CoA Transferase 1 (OXCT1))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OXCT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OXCT1 Antibody

Binding Specificity: N-Term

Sequence: TLAERIRAGG AGVPAFYTPT GYGTLVQEGG SPIKYNKDGS VAIASKPREV

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against OXCT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human OXCT1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 520 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for OXCT1

Target: OXCT1 (3-Oxoacid CoA Transferase 1 (OXCT1))

Alternative Name: OXCT1

Background: OXCT1 is a member of the 3-oxoacid CoA-transferase gene family. It is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate.This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.
Alias Symbols: OXCT, SCOT
Protein Interaction Partner: SUMO2, UBC, MDM2, THOP1, RBBP7, PTPN11, PTMS, NME1, IDH1, HSPD1, MAPK14, ADSS, MTPN, C12orf10, CBX3, C11orf58, WDR1, IQCB1, TMEM189, TMEM9, VMA21, S100A16, TMEM177, SCAF4, SEPT11, SDHAF2, TIMM9, TOR1AIP1, UBXN7, VAPB, SUCLA2, SUCLG1, UQCRFS1P1, UQCRFS1, T
Protein Size: 520

Molecular Weight: 52 kDa

Gene ID: 5019

NCBI Accession: NM_000436, NP_000427

UniProt: P55809

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis