GGPS1 antibody (Geranylgeranyl Diphosphate Synthase 1) (Middle Region)

Details for Product anti-GGPS1 Antibody No. ABIN2783409
Antigen
  • geranylgeranyl pyrophosphate synthase 1
  • DDBDRAFT_0192027
  • DDBDRAFT_0233098
  • DDB_0192027
  • DDB_0233098
  • GGPPS
  • GGPPS1
  • 1810026C22Rik
  • 9530089B04Rik
  • AI843169
  • C79210
  • Crlf3
  • rGGPS1a
  • rGGPS1a1
  • rGGPS1a2
  • rGGPS1a3
  • fb05f09
  • qm
  • wu:fb05f09
  • zgc:101591
  • zgc:56514
  • geranylgeranyl pyrophosphate synthase 1
  • geranylgeranyl pyrophosphate synthetase
  • geranyl pyrophosphate synthase
  • geranylgeranyl pyrophosphate synthase,chloroplastic
  • geranylgeranyl diphosphate synthase 1
  • geranylgeranyl diphosphate synthase 1 L homeolog
  • GGPS1
  • gGPS1
  • ggps1
  • Ggps1
  • ggps1.L
Epitope
Middle Region
16
12
9
9
9
9
8
8
7
4
2
2
2
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio)
116
46
24
2
2
2
2
2
1
1
1
1
Host
Rabbit
104
14
Clonality
Polyclonal
Conjugate
This GGPS1 antibody is un-conjugated
9
9
8
7
7
6
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
92
61
49
13
12
7
5
5
4
3
2
2
Options
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human GGPS1
Blocking Peptide Blocking peptide for this product available: ABIN977384
Sequence LGLFFQIRDD YANLHSKEYS ENKSFCEDLT EGKFSFPTIH AIWSRPESTQ
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
Characteristics This is a rabbit polyclonal antibody against GGPS1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Plasmids, Primers & others Plasmids, Primers & others GGPS1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name GGPS1 (GGPS1 Antibody Abstract)
Background GGPS1 is a member of the prenyltransferase family and has geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. The protein is an important precursor of carotenoids and geranylated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: GGPPS, GGPPS1
Protein Interaction Partner: GGPS1, ATOX1, UBC,
Protein Size: 300
Molecular Weight 35 kDa
Gene ID 9453
NCBI Accession NM_001037277, NP_001032354
UniProt O95749
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 300 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Image no. 1 for anti-Geranylgeranyl Diphosphate Synthase 1 (GGPS1) (Middle Region) antibody (ABIN2783409) WB Suggested Anti-GGPS1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Posi...
Background publications Raz, Nardi, Azam, Cortes, Daley: "Farnesyl transferase inhibitor resistance probed by target mutagenesis." in: Blood, Vol. 110, Issue 6, pp. 2102-9, 2007 (PubMed).

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