GSTA4 antibody (C-Term)

Catalog No. ABIN2783418

This Rabbit Polyclonal antibody specifically detects GSTA4 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Horse, Rabbit, Cow, Dog, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for GSTA4 antibody (C-Term) (ABIN2783418)

Target: GSTA4 (Glutathione S-Transferase alpha 4 (GSTA4))

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTA4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GSTA4 Antibody

Binding Specificity: C-Term

Purpose: GSTA4 Antibody - C-terminal region

Sequence: LSAFPFLQEY TVKLSNIPTI KRFLEPGSKK KPPPDEIYVR TVYNIFRP

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 77%, Rabbit: 100%, Rat: 79%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against GSTA4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GSTA4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48555-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GSTA4

Target: GSTA4 (Glutathione S-Transferase alpha 4 (GSTA4))

Alternative Name: GSTA4

Background:

Background Information: GSTA4 is a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Glutathione S-transferase alpha 4

Alternative Symbols: GTA4, GSTA4-4

Protein Name: Glutathione S-transferase A4

Molecular Weight: 26kDa

Gene ID: 2941

NCBI Accession: NP_001503

UniProt: O15217