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3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (Middle Region) antibody Primary Antibody

HMGCS1 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783421
$389.00
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100 μL
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  • Target
    3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1)
    Binding Specificity
    • 15
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 29
    • 23
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
    Host
    • 39
    • 3
    • 2
    Rabbit
    Clonality
    • 44
    Polyclonal
    Conjugate
    • 25
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    • 27
    • 16
    • 13
    • 13
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    Immunohistochemistry (IHC), Western Blotting (WB)
    Sequence
    KDFTLNDFGF MIFHSPYCKL VQKSLARMLL NDFLNDQNRD KNSIYSGLEA
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against HMGCS1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human HMGCS1
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 520 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1)
    Alternative Name
    HMGCS1 (HMGCS1 Antibody Abstract)
    Synonyms
    HMGCS, zgc:56481, B130032C06Rik, 3-hydroxy-3-methylglutaryl-CoA synthase 1, 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble), 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1, 3-hydroxy-3-methylglutaryl coenzyme A synthase, hydroxymethylglutaryl-CoA synthase, 3-hydroxy-3-methylglutaryl-CoA synthase, hydroxymethylglutaryl coenzyme A synthase, 3-hydroxy-3-methylglutaryl-CoA synthase 1 S homeolog, HMGCS1, hmgcs1, Hmgcs1, mvaS, SAS2432, SZO_RS04705, SEQ_1109, NAEGRDRAFT_77778, hmgcs1.S
    Background
    This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
    Alias Symbols: HMGCS, MGC90332
    Protein Interaction Partner: UBC, CLN5, SPDL1, SPG21, PEG10, MAPK9, PFN2, KARS, IARS, DARS,
    Protein Size: 520
    Molecular Weight
    57 kDa
    Gene ID
    3157
    NCBI Accession
    NM_002130, NP_002121
    UniProt
    Q01581
    Pathways
    Regulation of Lipid Metabolism by PPARalpha
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