Laminin beta 1 antibody (Middle Region)

Catalog No. ABIN2783423

Cited in 1 publication. The Rabbit Polyclonal anti-Laminin beta 1 antibody (ABIN2783423) specifically detects Laminin beta 1 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Pig and Saccharomyces cerevisiae samples.

Quick Overview for Laminin beta 1 antibody (Middle Region) (ABIN2783423)

Target: Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Laminin beta 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Laminin beta 1 Antibody

Binding Specificity: Middle Region

Purpose: LAMB1 Antibody - middle region

Sequence: VEELKRKAAQ NSGEAEYIEK VVYTVKQSAE DVKKTLDGEL DEKYKKVENL

Predicted Reactivity: Cow: 93%, Dog: 79%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 85%, Rat: 100%, Yeast: 75%

Characteristics: This is a rabbit polyclonal antibody against LAMB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LAMB1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48567-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-Laminin beta 1 antibody (ABIN2783423)

Puttabyatappa, Irwin, Martin, Mesquitta, Veiga-Lopez, Padmanabhan: "Developmental Programming: Gestational Exposure to Excess Testosterone Alters Expression of Ovarian Matrix Metalloproteases and Their Target Proteins" in: Reproductive sciences (Thousand Oaks, Calif.), pp. 1933719117697130, (2017) (PubMed).

Target Details for Laminin beta 1

Target: Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))

Alternative Name: LAMB1

Background:

Targeted Subunit: beta-1

Background Information: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, n

Gene Name: Laminin, beta 1

Alternative Symbols: CLM, LIS5

Protein Name: Laminin subunit beta-1

Molecular Weight: 198kDa

Gene ID: 3912

NCBI Accession: NP_002282

UniProt: P07942