HAT1 antibody (N-Term)

Catalog No. ABIN2783435

The Rabbit Polyclonal anti-HAT1 antibody has been validated for WB. It is suitable to detect HAT1 in samples from Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse and Rabbit.

Quick Overview for HAT1 antibody (N-Term) (ABIN2783435)

Target: HAT1 (Histone Acetyltransferase 1 (HAT1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HAT1 Antibody

Binding Specificity: N-Term

Sequence: FPEDLENDIR TFFPEYTHQL FGDDETAFGY KGLKILLYYI AGSLSTMFRV

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Hat1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Hat1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 419 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HAT1

Target: HAT1 (Histone Acetyltransferase 1 (HAT1))

Alternative Name: Hat1

Background: Hat1 acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Hat1 has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Hat1 may be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes.
Alias Symbols: MGC105743
Protein Size: 419

Molecular Weight: 46 kDa

Gene ID: 296501

NCBI Accession: NM_001009657, NP_001009657

UniProt: Q5M939