RABGGTB antibody (Middle Region)

Catalog No. ABIN2783444

The Rabbit Polyclonal anti-RABGGTB antibody is suitable to detect RABGGTB in samples from Human, Mouse, Rat, Cow, Dog, Rabbit, Sheep, Guinea Pig, Horse and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for RABGGTB antibody (Middle Region) (ABIN2783444)

Target: RABGGTB (Rab Geranylgeranyltransferase, beta Subunit (RABGGTB))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Sheep, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RABGGTB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RABGGTB Antibody

Binding Specificity: Middle Region

Purpose: RABGGTB Antibody - middle region

Sequence: PGDMVDPFHT LFGIAGLSLL GEEQIKPVNP VFCMPEEVLQ RVNVQPELVS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against RABGGTB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RABGGTB

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48634-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RABGGTB

Target: RABGGTB (Rab Geranylgeranyltransferase, beta Subunit (RABGGTB))

Alternative Name: RABGGTB

Background:

Targeted Subunit: beta

Background Information: RABGGTB catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively.

Gene Name: Rab geranylgeranyltransferase, beta subunit

Alternative Symbols: GGTB

Protein Name: Geranylgeranyl transferase type-2 subunit beta

Molecular Weight: 37kDa

Gene ID: 5876

NCBI Accession: NP_004573

UniProt: P53611