METTL1 antibody (Middle Region)

Catalog No. ABIN2783457

The Rabbit Polyclonal anti-METTL1 antibody (ABIN2783457) specifically detects METTL1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Goat and Zebrafish (Danio rerio) samples.

Quick Overview for METTL1 antibody (Middle Region) (ABIN2783457)

Target: METTL1 (Methyltransferase Like 1 (METTL1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Goat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METTL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-METTL1 Antibody

Binding Specificity: Middle Region

Purpose: METTL1 Antibody - middle region

Sequence: KGQLTKMFFL FPDPHFKRTK HKWRIISPTL LAEYAYVLRV GGLVYTITDV

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 87%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against METTL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human METTL1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48665-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for METTL1

Target: METTL1 (Methyltransferase Like 1 (METTL1))

Alternative Name: METTL1

Background:

Background Information: METTL1 contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation.This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X.

Gene Name: Methyltransferase like 1

Alternative Symbols: TRM8, TRMT8, C12orf1, YDL201w

Protein Name: tRNA (guanine-N(7)-)-methyltransferase

Molecular Weight: 34kDa

Gene ID: 4234

NCBI Accession: NP_005362

UniProt: Q9UBP6