Involucrin antibody (N-Term)

Catalog No. ABIN2783459

The Rabbit Polyclonal anti-Involucrin antibody is suitable to detect Involucrin in samples from Human and Cow. It has been validated for WB.

Quick Overview for Involucrin antibody (N-Term) (ABIN2783459)

Target: Involucrin (IVL)

Reactivity: Human, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Involucrin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Involucrin Antibody

Binding Specificity: N-Term

Purpose: IVL Antibody - N-terminal region

Sequence: AENPEQQLKQ EKTQRDQQLN KQLEEEKKLL DQQLDQELVK RDEQLGMKKE

Predicted Reactivity: Cow: 83%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against IVL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IVL

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48675-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Involucrin

Target: Involucrin (IVL)

Alternative Name: IVL

Background:

Background Information: Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase.Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Involucrin

Alternative Symbols: -

Protein Name: Involucrin

Molecular Weight: 68kDa

Gene ID: 3713

NCBI Accession: NP_005538

UniProt: P07476