LCMT2 antibody (C-Term)

Catalog No. ABIN2783497

The Rabbit Polyclonal anti-LCMT2 antibody is suitable to detect LCMT2 in samples from Human, Rat, Cow, Dog, Horse and Pig. It has been validated for WB.

Quick Overview for LCMT2 antibody (C-Term) (ABIN2783497)

Target: LCMT2 (Leucine Carboxyl Methyltransferase 2 (LCMT2))

Reactivity: Human, Rat, Cow, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LCMT2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LCMT2 Antibody

Binding Specificity: C-Term

Purpose: LCMT2 Antibody - C-terminal region

Sequence: PVLSDWHFLH VGTMAWVRIP VEGEVPEARH SHSACTWQGG ALIAGGLGAS

Predicted Reactivity: Cow: 86%, Dog: 86%, Horse: 86%, Human: 100%, Pig: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against LCMT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human LCMT2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104227

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for LCMT2

Target: LCMT2 (Leucine Carboxyl Methyltransferase 2 (LCMT2))

Alternative Name: LCMT2

Background:

Background Information: LCMT2 belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW). The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW).

Gene Name: Leucine carboxyl methyltransferase 2

Alternative Symbols: PPM2, TYW4

Protein Name: Leucine carboxyl methyltransferase 2

Molecular Weight: 75kDa

Gene ID: 9836

NCBI Accession: NP_055608

UniProt: O60294