AASDHPPT antibody (C-Term)

Catalog No. ABIN2783499

The Rabbit Polyclonal anti-AASDHPPT antibody (ABIN2783499) specifically detects AASDHPPT in WB. The antibody is reactive with Human, Rat, Cow, Dog, Horse, Guinea Pig, Pig and Rabbit samples.

Quick Overview for AASDHPPT antibody (C-Term) (ABIN2783499)

Target: AASDHPPT (Aminoadipate-Semialdehyde Dehydrogenase-phosphopantetheinyl Transferase (AASDHPPT))

Reactivity: Human, Rat, Cow, Dog, Horse, Guinea Pig, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AASDHPPT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AASDHPPT Antibody

Binding Specificity: C-Term

Purpose: AASDHPPT Antibody - C-terminal region

Sequence: SRHQDVPSQD DSKPTQRQFT ILNFNDLMSS AVPMTPEDPS FWDCFCFTEE

Predicted Reactivity: Cow: 79%, Dog: 86%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Pig: 93%, Rabbit: 86%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against AASDHPPT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AASDHPPT

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8094529

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for AASDHPPT

Target: AASDHPPT (Aminoadipate-Semialdehyde Dehydrogenase-phosphopantetheinyl Transferase (AASDHPPT))

Alternative Name: AASDHPPT

Background:

Background Information: AASDHPPT is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.

Gene Name: Aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

Alternative Symbols: ACPS, LYS2, LYS5, CGI-80, AASD-PPT

Protein Name: L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

Molecular Weight: 36kDa

Gene ID: 60496

NCBI Accession: NP_056238

UniProt: Q9NRN7