LIPT1 antibody (N-Term)

Catalog No. ABIN2783503

The Rabbit Polyclonal anti-LIPT1 antibody is suitable to detect LIPT1 in samples from Human, Mouse, Dog, Horse, Rat, Cow, Guinea Pig and Rabbit. It has been validated for WB.

Quick Overview for LIPT1 antibody (N-Term) (ABIN2783503)

Target: LIPT1 (Lipoyltransferase 1 (LIPT1))

Reactivity: Human, Mouse, Dog, Horse, Rat, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIPT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LIPT1 Antibody

Binding Specificity: N-Term

Purpose: LIPT1 Antibody - N-terminal region

Sequence: NCFQLLCNCQ VPAAGFKKTV KNGLILQSIS NDVYQNLAVE DWIHDHMNLE

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against LIPT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LIPT1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48784-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for LIPT1

Target: LIPT1 (Lipoyltransferase 1 (LIPT1))

Alternative Name: LIPT1

Background:

Background Information: The process of transferring lipoic acid to proteins is a two-step process. The first step is the activation of lipoic acid by lipoate-activating enzyme to form lipoyl-AMP. For the second step, LIPT1 transfers the lipoyl moiety to apoproteins.The process of transferring lipoic acid to proteins is a two-step process. The first step is the activation of lipoic acid by lipoate-activating enzyme to form lipoyl-AMP. For the second step, the protein encoded by this gene transfers the lipoyl moiety to apoproteins. Alternative splicing in the 5' UTR of this gene results in five transcript variants that encode the same protein.

Gene Name: Lipoyltransferase 1

Alternative Symbols: LIPT1D

Protein Name: Lipoyltransferase 1, mitochondrial

Molecular Weight: 42 kDa

Gene ID: 51601

NCBI Accession: NP_057013

UniProt: Q9Y234