TRMU antibody (N-Term)

Catalog No. ABIN2783514

The Rabbit Polyclonal anti-TRMU antibody is suitable to detect TRMU in samples from Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse and Pig. It has been validated for WB.

Quick Overview for TRMU antibody (N-Term) (ABIN2783514)

Target: TRMU (tRNA 5-Methylaminomethyl-2-Thiouridylate Methyltransferase (TRMU))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRMU antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRMU Antibody

Binding Specificity: N-Term

Purpose: TRMU Antibody - N-terminal region

Sequence: VCQILDIPFH QVSYVKEYWN DVFSDFLNEY EKGRTPNPDI VCNKHIKFSC

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TRMU. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TRMU

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48818-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRMU

Target: TRMU (tRNA 5-Methylaminomethyl-2-Thiouridylate Methyltransferase (TRMU))

Alternative Name: TRMU

Background:

Background Information: This gene is a member of the trmU family. It encodes a mitochondria-specific tRNA-modifying enzyme that is required for the 2-thio modification of 5-taurinomethyl-2-thiouridine tRNA-Lys on the wobble position of the anticodon.

Gene Name: tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase

Alternative Symbols: MTO2, MTU1, TRMT, LCAL3, TRMT1

Protein Name: Mitochondrial tRNA-specific 2-thiouridylase 1

Molecular Weight: 41kDa

Gene ID: 55687

UniProt: O75648