CROT antibody (N-Term)

Catalog No. ABIN2783539

The Rabbit Polyclonal anti-CROT antibody (ABIN2783539) specifically detects CROT in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit, Zebrafish (Danio rerio) and Saccharomyces cerevisiae samples.

Quick Overview for CROT antibody (N-Term) (ABIN2783539)

Target: CROT (Carnitine O-Octanoyltransferase (CROT))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CROT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CROT Antibody

Binding Specificity: N-Term

Purpose: CROT Antibody - N-terminal region

Sequence: MENQLAKSTE ERTFQYQDSL PSLPVPSLEE SLKKYLESVK PFANQEEYKK

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against CROT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CROT

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8096271

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CROT

Target: CROT (Carnitine O-Octanoyltransferase (CROT))

Alternative Name: CROT

Background:

Background Information: Carnitine octanoyltransferase is a carnitine acyltransferase that catalyzes the reversible transfer of fatty acyl groups between CoA and carnitine. This provides a crucial step in the transport of medium- and long-chain acyl-CoA out of the mammalian peroxisome to the cytosol and mitochondria.Carnitine octanoyltransferase (EC 2.3.1.137) is a carnitine acyltransferase that catalyzes the reversible transfer of fatty acyl groups between CoA and carnitine. This provides a crucial step in the transport of medium- and long-chain acyl-CoA out of the mammalian peroxisome to the cytosol and mitochondria. See also CRAT (MIM 600184). Van der Leij et al. (2000) [PubMed 11001805] reviewed the function, structural features, and phylogenetics of human carnitine acyltransferase genes, including CROT.[supplied by OMIM].

Gene Name: Carnitine O-octanoyltransferase

Alternative Symbols: COT

Protein Name: Peroxisomal carnitine O-octanoyltransferase

Molecular Weight: 70kDa

Gene ID: 54677

NCBI Accession: NP_066974

UniProt: Q9UKG9

Pathways: Monocarboxylic Acid Catabolic Process