GMPPB antibody (C-Term)

Catalog No. ABIN2783544

This Rabbit Polyclonal antibody specifically detects GMPPB in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig and Horse.

Quick Overview for GMPPB antibody (C-Term) (ABIN2783544)

Target: GMPPB (GDP-Mannose Pyrophosphorylase B (GMPPB))

Reactivity: Human, Mouse, Rat, Rabbit, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GMPPB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GMPPB Antibody

Binding Specificity: C-Term

Purpose: GMPPB Antibody - C-terminal region

Sequence: RCRVGQWVRM ENVTVLGEDV IVNDELYLNG ASVLPHKSIG ESVPEPRIIM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against GMPPB. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GMPPB

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101402

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GMPPB

Target: GMPPB (GDP-Mannose Pyrophosphorylase B (GMPPB))

Alternative Name: GMPPB

Background:

Background Information: GMPPB is a GDP-mannose pyrophosphorylase. This enzyme catalyzes the reaction which converts mannose-1-phosphate and GTP to GDP-mannose which is involved in the production of N-linked oligosaccharides.This gene is thought to encode a GDP-mannose pyrophosphorylase. This enzyme catalyzes the reaction which converts mannose-1-phosphate and GTP to GDP-mannose which is involved in the production of N-linked oligosaccharides. The gene encodes two transcript variants.

Gene Name: GDP-mannose pyrophosphorylase B

Alternative Symbols: LGMDR19, MDDGA14, MDDGB14, MDDGC14

Protein Name: Mannose-1-phosphate guanyltransferase beta

Molecular Weight: 43kDa

Gene ID: 29925

NCBI Accession: NP_037466

UniProt: Q9Y5P6