AGXT2 antibody (N-Term)

Catalog No. ABIN2783579

This Rabbit Polyclonal antibody specifically detects AGXT2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse and Rabbitand has been mentioned in 1 publication.

Quick Overview for AGXT2 antibody (N-Term) (ABIN2783579)

Target: AGXT2 (Alanine Glyoxylate Aminotransferase 2 (AGXT2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGXT2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AGXT2 Antibody

Binding Specificity: N-Term

Sequence: TSVTKLSLHT KPRMPPCDFM PERYQSLGYN RVLEIHKEHL SPVVTAYFQK

Predicted Reactivity: Cow: 86%, Dog: 79%, Horse: 79%, Human: 100%, Mouse: 77%, Rabbit: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against AGXT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AGXT2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 514 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-AGXT2 antibody (ABIN2783579)

Baker, Cramer, Kennedy, Assimos, Holmes: "Glycolate and glyoxylate metabolism in HepG2 cells." in: American journal of physiology. Cell physiology, Vol. 287, Issue 5, pp. C1359-65, (2004) (PubMed).

Target Details for AGXT2

Target: AGXT2 (Alanine Glyoxylate Aminotransferase 2 (AGXT2))

Alternative Name: AGXT2

Background: The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor.
Alias Symbols: AGT2, DAIBAT
Protein Interaction Partner: CYP2E1, ALDOB,
Protein Size: 514

Molecular Weight: 52 kDa

Gene ID: 64902

NCBI Accession: NM_031900, NP_114106

UniProt: Q9BYV1

Pathways: Monocarboxylic Acid Catabolic Process