GSTZ1 antibody (N-Term)

Catalog No. ABIN2783617

The Rabbit Polyclonal anti-GSTZ1 antibody is suitable to detect GSTZ1 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Goat and Pig. It has been validated for WB.

Quick Overview for GSTZ1 antibody (N-Term) (ABIN2783617)

Target: GSTZ1 (Glutathione Transferase zeta 1 (Maleylacetoacetate Isomerase) (GSTZ1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Goat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTZ1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GSTZ1 Antibody

Binding Specificity: N-Term

Purpose: GSTZ1 Antibody - N-terminal region

Sequence: MQAGKPILYS YFRSSCSWRV RIALALKGID YETVPINLIK DGGQQFSKDF

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 77%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against GSTZ1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GSTZ1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101706

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GSTZ1

Target: GSTZ1 (Glutathione Transferase zeta 1 (Maleylacetoacetate Isomerase) (GSTZ1))

Alternative Name: GSTZ1

Background:

Background Information: GSTZ1 is a member of the glutathione S-transferase (GSTs) super-family which are important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia.This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms.

Gene Name: Glutathione transferase zeta 1

Alternative Symbols: MAI, MAAI, MAAID, GSTZ1-1

Protein Name: Maleylacetoacetate isomerase

Molecular Weight: 24kDa

Gene ID: 2954

NCBI Accession: NP_665877

UniProt: O43708