STRADA antibody (C-Term)
Quick Overview for STRADA antibody (C-Term) (ABIN2783634)
Target
See all STRADA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Purpose
- STRADA Antibody - C-terminal region
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Sequence
- AEELTMSPSR SVANSGLSDS LTTSTPRPSN GDSPSHPYHR TFSPHFHHFV
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Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Sheep: 93%
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Characteristics
- This is a rabbit polyclonal antibody against LYK5. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human LYK5
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8112914
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- prevent freeze-thaw cycles
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Storage
- 4 °C,-20 °C
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Storage Comment
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- STRADA (STE20-Related Kinase Adaptor alpha (STRADA))
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Alternative Name
- STRADA
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Background
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Background Information: LYK5 belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily. It contains 1 protein kinase domain. LYK5 is a pseudokinase which, in complex with CAB39, binds to and activates STK11. It relocates STK11 from the nucleus to the cytoplasm and plays an essential role in STK11-mediated G1 cell cycle arrest.
Gene Name: STE20-related kinase adaptor alpha
Alternative Symbols: LYK5, PMSE, Stlk, STRAD, NY-BR-96, STRAD alpha
Protein Name: STE20-related kinase adapter protein alpha
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Molecular Weight
- 44kDa
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Gene ID
- 92335
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NCBI Accession
- NP_001003786
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UniProt
- Q7RTN6
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Pathways
- AMPK Signaling
Target
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