PIGW antibody (Middle Region)

Catalog No. ABIN311149

This Rabbit Polyclonal antibody specifically detects PIGW in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Guinea Pig and Horse.

Quick Overview for PIGW antibody (Middle Region) (ABIN311149)

Target: PIGW (Phosphatidylinositol Glycan W (PIGW))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIGW antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PIGW Antibody

Binding Specificity: Middle Region

Purpose: PIGW Antibody - middle region

Sequence: IALGITVLYQ LALDFTSLKR LILYGTDGSG TRVGLLNANR EGIISTLGYV

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PIGW. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PIGW

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108030

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PIGW

Target: PIGW (Phosphatidylinositol Glycan W (PIGW))

Alternative Name: PIGW

Background:

Background Information: Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. PIGW acts in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol.Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. PIGW acts in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol (Murakami et al., 2003 [PubMed 14517336]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-430 AK094752.1 1-430 431-1570 AB097818.1 376-1515 1571-2255 AK094752.1 1571-2255

Gene Name: Phosphatidylinositol glycan anchor biosynthesis, class W

Alternative Symbols: Gwt1, HPMRS5

Protein Name: Phosphatidylinositol-glycan biosynthesis class W protein

Molecular Weight: 57kDa

Gene ID: 284098

NCBI Accession: NP_848612

UniProt: Q7Z7B1

Pathways: Inositol Metabolic Process