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B3GALTL antibody (Middle Region)

B3GALTL Reactivity: Human, Mouse, Dog, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783666
  • Target See all B3GALTL Antibodies
    B3GALTL (beta 1,3-Galactosyltransferase-Like (B3GALTL))
    Binding Specificity
    • 2
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Dog, Rat
    Host
    • 11
    • 1
    Rabbit
    Clonality
    • 12
    Polyclonal
    Conjugate
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This B3GALTL antibody is un-conjugated
    Application
    • 5
    • 4
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    DYPKDYLSHQ VPISFHKHWN IDPVKVYFTW LAPSDEDKAR QETQKGFREE
    Predicted Reactivity
    Dog: 93%, Human: 100%, Mouse: 79%, Rat: 79%
    Characteristics
    This is a rabbit polyclonal antibody against B3GALTL. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human B3GALTL
    Top Product
    Discover our top product B3GALTL Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 498 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    B3GALTL (beta 1,3-Galactosyltransferase-Like (B3GALTL))
    Alternative Name
    B3GALTL (B3GALTL Products)
    Synonyms
    B3GLCT antibody, B3GTL antibody, B3Glc-T antibody, Gal-T antibody, beta3Glc-T antibody, Gm1057 antibody, beta 3-glucosyltransferase antibody, beta 3-glucosyltransferase L homeolog antibody, beta-3-glucosyltransferase antibody, B3GLCT antibody, b3glct antibody, b3glct.L antibody, B3glct antibody
    Background
    B3GALTL is the O-fucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. B3GALTL specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.B3GALTL is a beta-1,3-glucosyltransferase involved in the synthesis of the unusual O-linked disaccharide glucosyl-beta-1,3-fucose-O- found on the thrombospondin (see THBS1, MIM 188060) type-1 repeats (TSRs) of many biologically important proteins. Biosynthesis of glucosyl-beta-1,3-fucose-O- is initiated by protein O-fucosyltransferase-2 (POFUT2, MIM 610249), which attaches the fucosyl residue to a serine or threonine within the TSR. B3GALTL subsequently transfers the glucose onto TSR-fucose (Hess et al., 2008 [PubMed 18199743]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-270 DN999521.1 41-310 271-457 AB101481.1 161-347 458-467 DN999521.1 499-508 468-1217 AB101481.1 358-1107 1218-1279 DA290408.1 515-576 1280-1607 AB101481.1 1170-1497 1608-2495 AY190526.1 1498-2385 2496-3459 AY190526.1 2387-3350 3460-4071 AV728071.1 87-698 4072-4221 AA769548.1 1-150 c
    Alias Symbols: B3GTL, B3Glc-T, Gal-T, beta3Glc-T, B3GLCT
    Protein Interaction Partner: UBC, ELAVL1,
    Protein Size: 498
    Molecular Weight
    56 kDa
    Gene ID
    145173
    NCBI Accession
    NM_194318, NP_919299
    UniProt
    Q6Y288
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