Transglutaminase 5 antibody (C-Term)

Catalog No. ABIN2783673

The Rabbit Polyclonal anti-Transglutaminase 5 antibody (ABIN2783673) specifically detects Transglutaminase 5 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow and Horse samples.

Quick Overview for Transglutaminase 5 antibody (C-Term) (ABIN2783673)

Target: Transglutaminase 5 (TGM5)

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Transglutaminase 5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Transglutaminase 5 Antibody

Binding Specificity: C-Term

Purpose: TGM5 Antibody - C-terminal region

Sequence: VLKPQHQASI ILETVPFKSG QRQIQANMRS NKFKDIKGYR NVYVDFAL

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 85%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TGM5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TGM5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49208-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Transglutaminase 5

Target: Transglutaminase 5 (TGM5)

Alternative Name: TGM5

Background:

Background Information: TGM5 belongs to the transglutaminase superfamily, transglutaminase family. It catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. It contributes to the formation of the cornified cell envelope of keratinocytes. Defects in TGM5 are a cause of peeling skin syndrome acral type (APSS).

Gene Name: Transglutaminase 5

Alternative Symbols: TGX, PSS2, TGM6, TGMX, TGASE5, TGASEX

Protein Name: Protein-glutamine gamma-glutamyltransferase 5

Molecular Weight: 81kDa

Gene ID: 9333

NCBI Accession: NP_963925

UniProt: O43548