PCDHB14 antibody (Protocadherin beta 14) (Middle Region)

Details for Product anti-PCDHB14 Antibody No. ABIN2783731
Antigen
Epitope
Middle Region
10
10
8
2
1
1
Reactivity
Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
38
Host
Rabbit
35
3
Clonality
Polyclonal
Conjugate
This PCDHB14 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
26
17
17
17
13
6
1
Options
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human PCDHB14
Sequence YGKISYTFFH ASEDIRKTFE INPISGEVNL RSPLDFEVIQ SYTINIQATD
Predicted Reactivity Cow: 86%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 93%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against PCDHB14. It was validated on Western Blot.
Purification Affinity Purified
Antigen
Alternative Name PCDHB14 (PCDHB14 Antibody Abstract)
Background This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
Alias Symbols: PCDH-BETA14
Protein Size: 645
Molecular Weight 70 kDa
Gene ID 56122
NCBI Accession NM_018934, NP_061757
UniProt B4DPE2
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeat freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Image no. 1 for anti-Protocadherin beta 14 (PCDHB14) (Middle Region) antibody (ABIN2783731) Host: Rabbit Target Name: PCDHB14 Sample Type: HT1080 Whole cell lysates Antibody Dil...