TREM2 antibody (Middle Region)

Catalog No. ABIN2783734

The Rabbit Polyclonal anti-TREM2 antibody has been validated for WB. It is suitable to detect TREM2 in samples from Mouse, Human, Rat, Cow and Horse.

Quick Overview for TREM2 antibody (Middle Region) (ABIN2783734)

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Reactivity: Mouse, Human, Rat, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TREM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TREM2 Antibody

Binding Specificity: Middle Region

Sequence: FPGESESFED AHVEHSISRS LLEGEIPFPP TSILLLLACI FLIKILAASA

Predicted Reactivity: Cow: 83%, Horse: 92%, Human: 100%, Mouse: 77%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against TREM2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TREM2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 230 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TREM2

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Alternative Name: TREM2

Background: The protein encoded by this gene is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).
Alias Symbols: TREM-2, Trem2a, Trem2b, Trem2c
Protein Interaction Partner: TYROBP,
Protein Size: 230

Molecular Weight: 25 kDa

Gene ID: 54209

NCBI Accession: NM_018965, NP_061838

UniProt: Q9NZC2