DLL4 antibody (N-Term)

Catalog No. ABIN2783745

This anti-DLL4 antibody is a Rabbit Polyclonal antibody detecting DLL4 in WB. Suitable for Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Saccharomyces cerevisiae.

Quick Overview for DLL4 antibody (N-Term) (ABIN2783745)

Target: DLL4 (delta-Like 4 (DLL4))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLL4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DLL4 Antibody

Binding Specificity: N-Term

Sequence: QGSLAVGQNW LLDEQTSTLT RLRYSYRVIC SDNYYGDNCS RLCKKRNDHF

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 100%, Yeast: 82%

Characteristics: This is a rabbit polyclonal antibody against DLL4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DLL4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 685 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DLL4

Target: DLL4 (delta-Like 4 (DLL4))

Alternative Name: DLL4

Background: Notch ligands family members are characterized by a DSL domain, EGF repeats, and a transmembrane domain. DLL4 plays a role in the Notch signaling pathway. IT activates Notch-1 and Notch-4.This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC126344, hdelta2
Protein Interaction Partner: NOTCH1, NOTCH4,
Protein Size: 685

Molecular Weight: 72 kDa

Gene ID: 54567

NCBI Accession: NM_019074, NP_061947

UniProt: Q9NR61

Pathways: Notch Signaling